The Department of Medicine maintains a robust basic, translational and clinical research program through University Hospitals, Case Western Reserve University and the Louis Stokes Cleveland VA Medical Center. The opportunity for researchers to work collaboratively in seeking solutions for human health issues has never been greater. Case Western Reserve University Department of Medicine is committed to creating dynamic and ambitious partnerships that contribute to the well-being of people worldwide.

The Department of Medicine is recognized nationally and internationally for our discoveries in basic, translational and clinical research. With state of the art facilities, including the newly opened Iris S. and Bert L. Wolstein Research Building and over $65 million in public and private funding annually, the Department of Medicine remains at the forefront of medical research.


The Department of Medicine’s research mission, under the direction of Chairman Robert Salata, MD, is overseen by current Vice Chairman of Research, Thomas Hostetter, MD. Additionally, each Division Chief is charged with oversight and guidance for his or her division’s research efforts. Additionally, several research focused centers and institutes within or affiliated with the department are directed by the department's physicians: the Cardiovascular Research Institute is led by Marco Costa, MD, the Harrington Discovery Institute and Institute for Transformative Molecular Medicine is led by Jonathan Stamler, MD, and Mukesh Jain, MD, the Digestive Health Institute is led by Fabio Cominelli, MD, PhD, the AIDS Clinical Trials Unit is led by Michael Lederman, MD, PhD, and Stanton Gerson, MD, oversees the Case Comprehensive Cancer Center and the National Center for Regenerative Medicine. Central managerial responsibilities for the department’s research program are assigned conductedAaron Adams. Divisional staff provide support for pre-award and post-award activities.

Grant Financials

The department received nearly $63 million of research funding in academic year 2014-2015. This includes funding to faculty conducting research at UH, CWRU and the VA. CWRU and the VA are the primary recipients of federal research funding.

Award Recipient Source Amount
UH Federal $1,268,675
UH Industry $11,200,298
CWRU Federal $42,671,872
CWRU Non-Federal $6,761,460
VA Federal $1,026,771
Total: $62,929,076

With such a large portfolio of grants, there is a continuous cycle of grants that are concluding and new grants that are in the pipeline for funding.


The department maintains dedicated basic research space in several UH and CWRU buildings. CWRU funded research is conducted in 87,819 ft2 of designated CWRU space and 10,134 ft2 of designated UH Cleveland Medical Center space. UH funded research is generally conducted in clinical areas in space that is utilized for research, teaching and clinical activities. As the volume of research patient related activity varies, so does the amount of space identified as research space. In the 12 months ended May 31, 2015, the department utilized 50,444 ft2 of UH space for UH funded research.


As of June 30, 2015, the department included the following research personnel: 55 physician-scientists who received, on average, 50.7% of their salary from research efforts; 23 research-scientists (PhDs) who received, on average, 59.6% of their salary from grants; over 265 other research personnel supporting the principal investigators.