January 2013 Newsletter

Department of Medicine eNewsletter
January 2013
:: Department News
:: Department Events
:: Leadership Council Minutes
Publication of the Month

"KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival" by Goutham Narla, MD in Science Translational Medicine.

Recent Grand Rounds

"How to Not Get Sued or Lose" by Kim Bixenstine


"Treating Type 2 Diabetes in 2013" by Saul Genuth, MD


"How Palliative Care Can Help Patients and Decrease 30-Day Hospital Readmissions" by Charles Wellman, MD


"Medical Benefits of Acupuncture" by Anisha Durve, LAC

Leadership Council
January 2013

Chair ::

R. Walsh


Present ::

B. Arafah

K. Armitage

A. Askari

R. Bonomo

F. Cominelli

F. Creighton
C. Hoppel

T. Hostetter

M. Jain

A. Kistemaker

N. Meropol

R. Salata

K. Strohl

R. Walsh
J. Wright


Recorded by ::
A. Staruch
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department news report


Richard Walsh, MD will receive the 2013 Robert H. Williams Distinguished Chairman of Medicine Award from the Association of Professors in Medicine (APM). This is the most prestigious award in academic internal medicine and is presented annually to recognize a physician who has demonstrated outstanding leadership as a chair of a department of internal medicine at a medical school.

The criteria of the Williams Award Selections committee to bestow the honor include progress in the department's administration as well as contributions to education, research and patient care. Dr. Walsh will be presented with the award at APM Winter Meeting in February.




Division of Cardiovascular Medicine

Marco CostaMarco Costa, MD pioneered Parachute device for the treatment of heart failure through his clinical trial. CardioKinetix Inc. announced the enrollment of the first patients in PARACHUTE IV, the randomized clinical trial of the minimally invasive Parachute Ventricular Partitioning Device. Dr. Costa believes that the device will address the need for better treatment of patients suffering ischemic heart failure. A positive outcome of the trial would position Parachute as the primary therapy option for the treatment of heart failure.




Division of Gastroenterology

Madeleine Murphy, CNP, DNP was recently appointed to the Medical Advisory Committee of the American Liver Foundation, Heartland Division. She is also an invited speaker at the 28th National Conference of the American Academy of Nurse Practitioners to be held in June 2013, her talk is entitled "Viral Hepatitis: Current Recommendations for Screening and Management."








Division of General Internal Medicine & Geriatrics


Thomas Hornick, MD, Elizabeth Fine Smilovich, MD and Scott Ober, MD were awarded a $264,500 grant for an Early Transitional Care Program. The program is concentrated on extended care provided by geriatric nurse practitioner and social worker to elderly veterans discharged from hospital as part of a Home Based Primary Care Program.
In addition, Dr. Fine Smilovich received a $100,000 grant for an Interdisciplinary Delirium Resource Team designed to improve delirium assessment, management, prevention, and follow-up.
Goutham Narla, MD and his team identified a gene marker responsible for the spread of breast cancer. The finding lays the foundation for predicting which patients develop more aggressive forms of cancer and developing personalized care. The new study examining KLF6-SV1 mutant gene entitled "KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival" was published in Science Translational Medicine.

Susan Padrino, MD was promoted to Assistant Dean for Clinical Education at the School of Medicine.







Division of Hematology & Oncology

Erica Campagnaro, MD was awarded a $10,000 grant from CTSC for project entitled "Oncology Nurses' Barriers to Discussion of Clinical Trial Therapy with Cancer Patients - Qualitative Analyses and Instrument Development."







Brenda Cooper, MD was appointed Clinical Medical Director of the University Hospitals Seidman Cancer Center Adult Hematologic Malignancies and Stem Cell Transplant Program. The new position is the acknowledgement of Dr. Cooper's multiple contributions to the program, including her continuous involvement in patient care, clinical leadership and research.





The findings of Cheng-Kui Qu, MD and Stanton Gerson, MD were published an article entitled "Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation" in Cell Stem Cell Journal. The work uncovers a previously unknown mitochondrial metabolic regulation in hematopoietic stem cell differentiation and self-renewal, which represents a conceptual advance in the field. The association between mitochondrial metabolism and stem cell function demonstrated in the paper has widespread relevance to the study of stem cells, aging, cancer and metabolism.


Neelesh Sharma, MD was awarded a CTSC grant in the amount of $50,000 for his project entitled "Microarray Gene Expression Analyses to Identify Pharmacodynamic Marker of Erlotinib and Quinacrine in Non-Small Cell Lung Cancer."










Division of Infectious Diseases & HIV Medicine

Charles Bark, MD, MS, research fellow in the TB Research Unit at Case Western Reserve University, was named a Clinical and Translational Research Scholar. Dr. Bark's research focuses on biomarkers of response to anti-TB treatment and clinical testing of new drugs and drug combinations for TB treatment.


Robin Jump, MD, PhD was selected to become a CWRU VA Clinical Research Scholar for her research proposal entitled "A Diagnostic Test to Identify People at Risk for Recurrent C. Difficile Infection." Dr. Jump will start the Clinical Research Scholar program in June 2013.






The Infectious Diseases Alliance together with the Cleveland Department of Public Health introduced a Teen Night at J. Glen Smith Health Center. The new initiative will offer low-cost, confidential medical services for teens. The services will include reproductive health check-ups, STI testing, HPV vaccinations, pregnancy testing, family planning and contraceptive services. In addition, the Infectious Diseases Alliance will be holding educational sessions focused on STI prevention at St. Martin de Porres Family Center in Glenville, OH. The Infectious Diseases Alliance's work in community will be presented at the Society for Public Health Education's Annual Meeting in the talk entitled "Empowering Urban Youth to Take the Lead in Sexual Health Education: A Collaborative, Community-Based Approach in Cleveland, Ohio."




Division of Nephrology & Hypertension


Donald Hricik, MD published his second novel entitled "Nothing to Confess." The fictional medical mystery poses the question of a medical mistake by following the story of a deceased donor who provides organ transplants for seven recipients in Ohio, Michigan and Pennsylvania. Two months later, six of the recipients are either dead or in persistent vegetative states. As investigations unfold, careers and reputations of medical personnel, public trust in the organ donation system, and the lives of patients awaiting organ transplants are in jeopardy.


department conferences & events

Medicine Grand Rounds

Location: Kulas Auditorium

Time: 12:00 - 1:00 p.m.

  • February 5 - "Colon Cancer Screening" by Gregory Cooper, MD, Division of Gastroenterology
  • February 12 - "AAA and EVAR as well as TVAR" by Vikram Kashyap, MD, FACS, Department of Surgery
  • February 19 - "Role of Immune Activation and Inflammation in HIV Pathogenesis and Clinical Outcomes" by Michael Lederman, MD, Division of Infectious Diseases and HIV Medicine
  • February 26 - "Neurocognitive Aspects of Cardiovascular Disease" by John Gunstad, PhD, Department of Psychology, Kent State University
Research Retreat 2013
Date: Saturday, February 9, 2013
Time: 7:30 a.m. - 1:30 p.m.
Location: Wolstein Research Building, 2103 Cornell Road, Cleveland, OH 44106
department leadership council minutes

Leadership CouncilDr. Walsh updated council members on the current recruitments for the Chairs of Genetics, Epidemiology and Biostatistics and Ophthalmology at CWRU/UHCMC as well as the search for the new UHHS Chief Operating Officer.

Leadership Council

Dr. Armitage gave an overview of the Leadership Academy, of which he is a participant.



Leadership Council

Dr. Cominelli reported on the monthly strategic planning meeting for the hospital which is led by Mr. Zenty. The meeting in January focused on communication between system leadership and faculty members/staff. Dr. Walsh will invite Mr. Zenty to speak to the faculty at a special Grand Rounds presentation in the near future.


Leadership Council

Mr. Creighton reviewed the 2012 Clinical Incentive Metrics for the Department of Medicine. Dr. Walsh requested input from the Division Chiefs regarding the criteria for these incentives in order to finalize the 2013 Clinical Incentive Metrics at next month's Leadership Council meeting.



Dr. Bonomo updated the council on the activities at the Louis Stokes Cleveland Veterans Affairs Medical Center regarding grant submissions, number of merit awards and faculty recruitments. The current faculty openings include:Women's Health Director, Renal Section Chief, and two clinical positions, one in Cardiovascular Medicine and one in the Renal Section.

Leadership Council

Dr. Salata announced that there will be a Department of Medicine Research Retreat on Saturday, February 9, 2013 from 7:30 a.m. to 1:30 p.m. at the Wolstein Research Building. He distributed the retreat agenda including details on two Plenary Sessions and four Breakout Sessions. Additional information and registration details are available under "Research" tab on the Department of Medicine website, http://medicine.case.edu/